Almost everyone uses Dropbox these days. If you care about looks, you will probably want to change the icons. Unfortunately, there is no way (that I know of) to change the notification area icon, but the default icons used in Nautilus to display the status of each file can easily be changed. Charles A. @ Dropbox forums posted some beautiful Tango icons
When you want to customize the look and feel of your Linux desktop environment, you can find many resources for altering window managers and interface widgets, but working with icons has always been more of an issue. Now you can get help with icons from a new program called Tango Generator.